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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
19.7
Human Site:
S308
Identified Species:
30.95
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
S308
S
L
V
A
K
A
Q
S
L
P
S
D
Q
P
V
Chimpanzee
Pan troglodytes
XP_510301
627
67581
P287
N
L
Y
L
P
Q
D
P
T
V
A
K
G
A
L
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
S308
S
L
V
A
K
A
Q
S
L
P
S
D
Q
P
V
Dog
Lupus familis
XP_544614
968
105825
S595
S
L
V
A
K
A
Q
S
L
P
S
D
Q
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
S309
N
L
V
A
K
A
Q
S
L
P
S
E
Q
P
M
Rat
Rattus norvegicus
Q62829
544
60692
R204
H
T
K
S
I
Y
T
R
S
V
V
E
S
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
S299
P
A
S
A
Y
P
S
S
G
S
L
H
R
P
P
Chicken
Gallus gallus
XP_426393
667
74767
R308
Q
P
T
S
D
F
P
R
L
I
S
D
A
G
T
Frog
Xenopus laevis
NP_001082100
650
73749
S303
L
D
S
K
S
S
V
S
K
G
S
S
R
P
Q
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
S308
F
L
H
S
G
T
S
S
P
L
V
S
G
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
H299
N
P
L
H
P
H
A
H
P
H
P
H
H
H
Q
Honey Bee
Apis mellifera
XP_001122147
624
70155
S284
P
K
I
S
P
V
G
S
I
A
S
Q
R
P
L
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
P232
D
I
V
P
P
A
I
P
D
R
P
A
R
T
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
L459
N
H
V
M
S
P
T
L
N
T
D
S
S
S
A
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
G457
F
P
Q
V
G
H
E
G
S
F
E
N
P
R
A
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
80
0
N.A.
20
20
20
13.3
N.A.
0
20
13.3
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
13.3
N.A.
26.6
26.6
33.3
20
N.A.
13.3
53.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
34
0
34
7
0
0
7
7
7
7
7
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
7
0
7
0
7
0
7
27
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
0
0
0
7
14
0
0
0
% E
% Phe:
14
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
14
0
7
7
7
7
0
0
14
14
0
% G
% His:
7
7
7
7
0
14
0
7
0
7
0
14
7
7
0
% H
% Ile:
0
7
7
0
7
0
7
0
7
7
0
0
0
7
0
% I
% Lys:
0
7
7
7
27
0
0
0
7
0
0
7
0
0
0
% K
% Leu:
7
40
7
7
0
0
0
7
34
7
7
0
0
0
20
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
14
% M
% Asn:
27
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% N
% Pro:
14
20
0
7
27
14
7
14
14
27
14
0
7
47
7
% P
% Gln:
7
0
7
0
0
7
27
0
0
0
0
7
27
0
14
% Q
% Arg:
0
0
0
0
0
0
0
14
0
7
0
0
27
7
7
% R
% Ser:
20
0
14
27
14
7
14
54
14
7
47
20
14
7
0
% S
% Thr:
0
7
7
0
0
7
14
0
7
7
0
0
0
7
7
% T
% Val:
0
0
40
7
0
7
7
0
0
14
14
0
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _